For a large number of problems
there will be some animal of choice, on which
it can be most conveniently studied.

-August Krogh

Using the comparative approach to study the effect of environmental extremes in temperature, oxygen, hydrostatic pressure & salinity on physiological processes, including:

• Enzyme kinetics & adaptation
• Heat shock protein expression & regulation
• Genome-level response with microarrays
• Metabolic rate & acclimation
• Osmolyte and membrane composition & chemistries